GETTING MY FRACTAL STORM (SELF-LAID TO WORK

In the LSD-bound crystal framework, the aspect chain with the lid residue L209EL2 forms comprehensive hydrophobic contacts with the two LSD and encompassing residues in TMs III, IV, and V (Determine 4C). If the lid moved apart to expose the binding pocket in simulation, several of those contacts broke. We So hypothesized that L209EL2 acts to be a l